The Minimally Invasive Step: An Algorithm for Postoperative Complications

Document Type : Original Article

Authors
Department of General Surgery, N.V. Sklifosovsky Institute of Clinical Medicine of I.M. Sechenov First Moscow State Medical University, 119146, Moscow, Russia.
10.24271/psr.2026.578497.2640
Abstract
Postoperative intra-abdominal complications (POIACs) are a major challenge in abdominal surgery, associated with high morbidity and mortality. However, no clinically validated algorithms exist to guide the critical decision between laparoscopic and open surgical access. This single-center cohort study analyzed 253 patients with POIACs. We evaluated the prognostic significance of universal scales (SAPS II, SOFA, APACHE II), peritonitis-specific scores (Mannheim Peritonitis Index (MPI), Surgical Strategy for Peritonitis Scale (SSPS), World Society of Emergency Surgery Sepsis Severity Score (WSES SSS), Abdominal Cavity Index (ACI)), and laboratory markers (procalcitonin (PCT), lactate, C-reactive protein (CRP)) using ROC analysis and binary logistic regression. Independent predictors for selecting open access included age ≥60 years, ASA ≥ IV, SAPS II ≥ 28, SOFA ≥ 4, and APACHE II ≥ 17. For peritonitis, key thresholds were SSPS ≥ 4 (OR 1.69) and MPI ≥ 21 (OR 1.08). The combined criterion of PCT ≥7 ng/mL and lactate ≥2 mmol/L demonstrated high specificity (85%) for predicting laparotomy. Based on these findings, a three-zone risk stratification algorithm ("green," "yellow," "red") was developed. Application of the laparoscopic approach, guided by these criteria, led to significantly better outcomes, including a dramatic reduction in 90-day mortality for infectious complications (1.1% vs. 15.1%, p<0.001). Crucially, successful laparoscopic correction after primary laparotomy ("minimally invasive step") was achieved in 48.7% of patients with peritonitis and 63.5% with non-infectious complications. This algorithm provides a validated, quantitative framework for selecting surgical access in POIACs, potentially improving patient outcomes by optimizing the surgical approach. The concept of a "minimally invasive step" challenges the dogma of mandatory repeat laparotomy after primary open surgery.
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